Fairness-Kaufhaus Kaiserslautern
Beethovenstraße 56
67655 Kaiserslautern
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Pros: open six days a week, to include evenings and Saturdays; non-profit organization that supports the community; courtyard where donors can drive in to drop off donations; accepts non-expired human and pet food, cleaning supplies, and health/beauty products as part of the Foodsharing project
Cons: Limited space for accepting furniture; paid streetside parking for shopping (though usually it's not too hard to find a spot)
Notes: this is my favorite thrift store in the area. Although it's not the biggest, there's a decent selection of homewares, clothing, and furniture (keep in mind that the furniture sells quickly though; if you see a sign on it that says "verkauft," that means it's sold). Even better yet is that Fairness is a pick-up/drop-off point for Foodsharing KL, which is free for everyone to use. You can bring or take unexpired food (even for pets!), as well as cleaning supplies and health/beauty items. When you're PCSing, don't throw away all those cleaners; bring them to Fairness instead. Currently the Foodsharing drop off area is located by the door to the courtyard. When you walk into the store, walk straight ahead, past the cashier, and there's a cooler. You can put items in the cooler or on top of it.
Schatzkiste
Pariser Strasse 28 67655 Kaiserslautern
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Cons: none that I can think of.
Notes: Schatzkiste is a huge warehouse near the mall in downtown Kaiserslautern. There is always something new to see or buy, but keep in mind that the furniture turns over very quickly.
DRK Store
Rummelstr. 1 67655 Kaiserslautern
Website
Pros: open six days a week, to include evenings and Saturdays; non-profit organization that supports the community; quality merchandise
Cons: parking is paid, streetside, and somewhat limited (you could use the garage at Stiftsplatz though); only better quality merchandise is sold/accepted; no furniture and limited household items acceptance
Notes: if you're looking to buy some nicer clothing, including new items donated by the manufacturer (including new t-shirts donated by Fruit of the Loom), this is a good place to look. This is the smallest store of the bunch and is in the heart of downtown. Next to the weekly Farmers Market (which is open Tuesdays and Saturdays 0700-1300 year-round), it's a fun stop after buying your groceries.
Stadtbildpflege donation bins around Kaiserslautern
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Pros: open 24/7; any clean clothing, bedsheets, purses, belts, blankets, and shoes can be dropped off in a plastic bag, even if it has holes or broken parts (it will be recycled into something else); various locations throughout the city and one can normally park directly in front of the bins
Cons: only accepts the items above; sometimes the bins are full